(Ξένη δημοσίευση)- ΑΝΑΚΟΙΝΩΣΗ ΤΥΠΟΥ- SAKELLAROPOULOS ORGANIC FARMS - Olives by Sakellaropoulos Organic Farms in a dietary supplement
ΑΝΑΚΟΙΝΩΣΕΙΣ ΤΥΠΟΥ / Τετάρτη 9 Απριλίου 2025, 09:28 / Πηγή: SAKELLAROPOULOS ORGANIC FARMS
Olives by Sakellaropoulos Organic Farms in a dietary supplement
To reduce cholesterol and protect the cardiovascular system
The peer-reviewed article titled "Reduction of LDL and Total Cholesterol Levels with Kalamata Table Olive Extract: A Natural Approach to Dyslipidemia" was published in the scientific journal International Journal of Functional Nutrition.
This publication is part of an ongoing series of studies examining the health benefits of high-phenolic organic olives from Sakellaropoulos Olive Groves. These earlier studies laid the groundwork for the development of an innovative dietary supplement aimed at managing cholesterol, called CHOLESTOLIVE.
During the process, researchers reviewed 150 different types and qualities of table olives from across Greece. Eventually, organic Kalamata table olives from Sakellaropoulos Olive Groves in Sparta were selected, as they contained the highest levels of key phenols, such as hydroxytyrosol and tyrosol.
The unique composition of these olives, rich in phenolic compounds, has demonstrated beneficial effects on lipid profiles, as shown in studies conducted at the National and Kapodistrian University of Athens from 2014 to the present. These studies involved both healthy individuals and those with borderline high cholesterol or subclinical dyslipidemia. In cases where lipid profiles were imbalanced, attending physicians assessed that incorporating the supplement into their routine, along with dietary adjustments, could delay—or even prevent—the need for pharmacotherapy.
Dr. Prokopis Magiatis, Associate Professor at the Department of Pharmacognosy and Chemistry of Natural Products at the National and Kapodistrian University of Athens, said:
"Table olives are an important part of the Mediterranean diet, but they’ve often been overlooked. The results of our studies, especially the latest one, confirm the effort made by scientists to highlight how table olives can benefit health. The Kalamata olives we used in these studies showed a significant ability to lower cholesterol levels, helping to protect the cardiovascular system. One key finding was that the dietary supplement made from these olives kept much of their health benefits. This shows that the polyphenols, extracted from the olives and included in the capsules, are the main contributors to their positive effects.It’s important to note that neither olives nor the supplement are a substitute for medication to treat hyperlipidemia. However, the study showed that they could be used by people with borderline high cholesterol, alongside a proper diet, as a natural way to help manage their cholesterol."
According to Nikos Sakellaropoulos, M.Sc Chemical Engineer and co-owner/production manager of Sakellaropoulos Organic Olive Groves, these olives are fully organic and unpasteurized. They’re made through a natural fermentation process, with no chemical additives or preservatives. Their outstanding taste and quality have been recognized through numerous international awards.
What really sets these olives apart are their phenol levels—specifically hydroxytyrosol and tyrosol—which are significantly higher than those typically found in olives. These compounds are well-known for their antioxidant and heart-protective properties. Research conducted by the Nationas and Kapodistrian University of Athens (UOA) between 2014 and 2024 highlights this unique advantage.
In fact, Nuclear Magnetic Resonance (NMR) analyses reveal that these olives contain over 1850 mg of phenols per kilogram. That means eating just 2 or 3 grams of olives daily provides more than 5 mg of these beneficial compounds—equivalent to consuming 20 grams of olive oil classified as protecting blood lipids from oxidation, in accordance with EU Regulation 432/2012.
Sakellaropoulos Organic Olive Groves is setting new standards for nutrition and innovation, blending tradition with scientific precision to create a product loved by consumers and recognized globally. These are the main reasons why the organic Kalamata olives from Sakellaropoulos Organic Olive Groves were chosen for clinical research. Over the past eleven years, the groves have provided large amounts of their organic olives for three clinical studies. These olives also played an important role in creating a dietary supplement in capsule form, expanding their health benefits.
From 2014 to 2016, the first observational study explored the effects of these table olives on healthy volunteers. It was the first study worldwide to demonstrate how olive consumption can improve lipid profiles, showcasing the positive impact on participants' health. The findings were presented at the International Society of Oleocanthal Conference on June 2-3, 2016, held at the International Olympic Academy in Olympia, Greece.
Building on these promising results, a second, more extensive study was conducted between 2017 and 2022. This study focused on patients with borderine hyperlipidemia and examined the daily consumption of Kalamata olives and its effect on their lipid profiles. The research involved leading institutions in Greece, including the Hypertension Unit of the First University Cardiology Clinic at Hippocrates General Hospital, directed by Professor Konstantinos Tsioufis, and the Biopathology Laboratory at the 401 General Military Hospital, led by Mr. Konstantinos Liaskonis. Under the guidance of Professor Nikolaos Drakoulis from the UOA Pharmacy Department, the study included 94 participants, 71 of whom completed it successfully. This research revealed the remarkable health benefits of these olives and opened the door for further studies and practical applications, such as developing dietary supplements in capsule form.
The olives used in the second observational study were “Valsamikes Kalamata olives” from Sakellaropoulos Organic Olive Groves in Sparta. These olives contained impressive amounts of hydroxytyrosol (1300 mg/kg) and tyrosol (560 mg/kg). Participants consumed five olives daily, providing 25 mg of hydroxytyrosol and 10 mg of tyrosol. The results of this study were published in the World Olive Center for Health’s annual report in May 2022.
The success of the first two studies inspired researchers at the Pharmacy Department of the University of Athens to take things a step further. They transformed the olives into powdered capsules under an internationally patented process, leading to the third clinical study. This study focused on patients with hyperlipidemia, who consumed two capsules of CHOLESTOLIVE dietary supplement daily. Produced from the phenol-rich organic Kalamata olives of Sakellaropoulos Olive Groves, the supplement was officially registered with the National Organization for Medicines in Greece (Registration No. 94522/08-09-2022).
The production of the CHOLESTOLIVE supplement and the clinical research were funded by the German company Mediakos GmbH, which holds the patent and commercial rights to the product. Encouraging results from the third study led to its expansion in April 2023, including more participants with borderline hyperlipidemia who were not undergoing medical treatment.
The third observational study, conducted between 2021 and 2024, focused on patients with hyperlipidemia who took two capsules of the CHOLESTOLIVE dietary supplement daily. This supplement, registered with the National Organization for Medicines in Greece, is made from “Plus Health Kalamata Olives” by Sakellaropoulos Organic Olive Groves, which have significantly higher phenol content compared to average table olives.
The study's findings were published in February 2025 in the International Journal of Functional Nutrition under the Greek title: “Reduction of LDL and Total Cholesterol Levels with Kalamata Table Olive Extract: A Natural Approach to Dyslipidemia”.
This research examined how phenol-rich Kalamata olives, in supplement form, affected lipid levels in individuals with mild dyslipidemia. The CHOLESTOLIVE capsules, equivalent to consuming five olives daily, were produced using a special process. This involved removing the oil, extracting compounds like tyrosol, hydroxytyrosol, and lactic acid, and then eliminating water and salt. Over 30 days, volunteers with mild dyslipidemia took two capsules daily while maintaining a healthy lifestyle and diet. The results showed a notable reduction in total cholesterol (4.16%) and LDL cholesterol (5.67%), with no changes observed in HDL cholesterol levels throughout the study.
These findings suggest that CHOLESTOLIVE can effectively lower total and LDL cholesterol levels, highlighting the potential health benefits of phenolic compounds found in table olives—especially hydroxytyrosol and tyrosol, which are linked to cardiovascular and metabolic health.
The high-phenol Kalamata Plus Health Olives from Sakellaropoulos Organic Olive Groves have gained recognition for their potential health benefits. Since March 2022, Yale University's School of Public Health, in collaboration with researchers from its Medical School's Cardiology Department, has been conducting a clinical study titled "Olives for Health". This research examines the impact of daily olive consumption on human health.
The "Olives for Health" project is officially registered under the identifier NCT05218980 in ClinicalTrials.gov, a global database maintained by the National Library of Medicine (NLM) at the National Institutes of Health (NIH) in the United States. This registration underscores the study's significance and its reach across 220 countries.
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